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CLOVER MS DATA ANALYSIS SOFTWARE TIMELINE

Timeline

2022
January 10

Major version v5 FTIR support

  • Fourier transform infrared (FTIR) format is now supported
  • The platform now allows work with infrared spectroscopy data in all modules
  • FTIR Specific preprocessing steps added
2021
October 18

Minor version v4.5

  • ROC curves added in all modules
  • Precision-Recall curves added in all modules
July 19

Occurrence of the p019 Gene in the blaKPC-Harboring Plasmids: Adverse Clinical Impact for Direct Tracking of KPC-Producing Klebsiella pneumoniae by Matrix-Assisted Laser Desorption Ionization–Time of Flight Mass Spectrometry

June 18

An Improved Matrix-Assisted Laser Desorption Ionization–Time of Flight Mass Spectrometry Data Analysis Pipeline for the Identification of Carbapenemase-Producing Klebsiella pneumoniae

June 3

Detection of azole resistance in Aspergillus fumigatus complex isolates using MALDI-TOF mass spectrometry

June 1

Multicenter Performance Evaluation of MALDI-TOF MS for Rapid Detection of Carbapenemase Activity in Enterobacterales: The Future of Networking Data Analysis With Online Software

May 7

Video Tutorials Release

 

February 15

Major version v4 Validation Module

  • Validation Module added
    • Now all models can be validated easily
    • Results can be downloaded as .csv
    • Resulting plots can be download as images
January 24

Rapid and Reproducible MALDI-TOF-Based Method for the Detection of Vancomycin-Resistant Enterococcus faecium Using Classifying Algorithms

2020
December 2

Implementation of MALDI-TOF Mass Spectrometry and Peak Analysis: Application to the Discrimination of Cryptococcus neoformans Species Complex and Their Interspecies Hybrids

September 28

Minor version v3.5.10 K-Nearest Neighbors

  • K- Nearest Neighbors (KNN) added
  • Neighborhood Components Analysis (NCA) added in KNN module
March 24

Minor version v3.5 Carbapenemases detection

  • Carbapenemases detection module added for specific institutions
  • FAQ´s section added
2019
September 16

Major version v3 Random Forest Analysis

  • Random Forest (RF) Analysis added
  • Module for blind sample identification added
February 18

Minor version v2.5

  • Biomarker analysis module added
  • Reproducibility analysis improvements
  • Metrics for K-Fold validation added
    • F1 score
    • Clinical scores
    • Classification scores
  • Feature importances added in all analysis
2018
November 12

Major Version v2 Support Vector Machine Analysis

  • Support Vector Machine (SVM) Analysis added
  • MALDI-TOF Bruker© format support added
  • K-fold cross validation added
  • Categories section added for studies
June 4

Minor version v1.5

  • Reproducibility Analysis Module implementation
  • Peak findings improvements
  • Preprocessing improvements
    • Variance stabilization added
    • Mass filtering improvements
  • Alignment improvements
  • Automatic replication spectra added
April 2

Major Version v0.1 PLS-DA Module

  • Partial Least Squares Discriminant Analysis (PLS-DA) implementation
  • MALDI-TOF open format support improvements
  • Hierarchical Clustering (HC) improvements
  • Principal Components Analysis (PCA) improvements
  • Smoothing added
  • Baseline subtraction added
March 1

Official Release of RUO Clover Software

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