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TIMELINE & CHANGELOG


Timeline

2022
July 7
Major version v0.6 LightGBM Algorithm
  • Light Gradient Boosting Machine (LightGBM) algorithm added
  • Shapley Values analysis section added in Random Forest and LightGMB algorithms
  • Confidence ellipses now can be displayed at PCA Analysis
  • SVG vector image format added. Now plots and charts can be downloaded as .svg
January 10
Major version v0.5 FTIR support
  • Fourier transform infrared (FTIR) format is now supported
  • The platform now allows work with infrared spectroscopy data in all modules
  • FTIR Specific preprocessing steps added
2021
October 18
Minor version v0.4.5
  • ROC curves added in all modules
  • Precision-Recall curves added in all modules
July 19
Occurrence of the p019 Gene in the blaKPC-Harboring Plasmids: Adverse Clinical Impact for Direct Tracking of KPC-Producing Klebsiella pneumoniae by Matrix-Assisted Laser Desorption Ionization–Time of Flight Mass Spectrometry

https://doi.org/10.1128/JCM.00238-21

June 18
An Improved Matrix-Assisted Laser Desorption Ionization–Time of Flight Mass Spectrometry Data Analysis Pipeline for the Identification of Carbapenemase-Producing Klebsiella pneumoniae

https://doi.org/10.1128/JCM.00800-21

June 3
Detection of azole resistance in Aspergillus fumigatus complex isolates using MALDI-TOF mass spectrometry

https://doi.org/10.1016/j.cmi.2021.06.005

June 1
Multicenter Performance Evaluation of MALDI-TOF MS for Rapid Detection of Carbapenemase Activity in Enterobacterales: The Future of Networking Data Analysis With Online Software

https://doi.org/10.3389/fmicb.2021.789731

May 7
Video Tutorials Release

 

February 15
Major version v0.4 Validation Module
  • Validation Module added
    • Now all models can be validated easily
    • Results can be downloaded as .csv
    • Resulting plots can be download as images
January 24
Rapid and Reproducible MALDI-TOF-Based Method for the Detection of Vancomycin-Resistant Enterococcus faecium Using Classifying Algorithms

https://doi.org/10.3390/diagnostics12020328

2020
December 2
Implementation of MALDI-TOF Mass Spectrometry and Peak Analysis: Application to the Discrimination of Cryptococcus neoformans Species Complex and Their Interspecies Hybrids

https://doi.org/10.3390/jof6040330

September 28
Minor version v0.3.5 K-Nearest Neighbors
  • K- Nearest Neighbors (KNN) added
  • Neighborhood Components Analysis (NCA) added in KNN module
March 24
Minor version v0.3.5 Carbapenemases detection
  • Carbapenemases detection module added for specific institutions
  • FAQ´s section added
2019
September 16
Major version v0.3 Random Forest Analysis
  • Random Forest (RF) Analysis added
  • Module for blind sample identification added
February 18
Minor version v0.2.5
  • Biomarker analysis module added
  • Reproducibility analysis improvements
  • Metrics for K-Fold validation added
    • F1 score
    • Clinical scores
    • Classification scores
  • Feature importances added in all analysis
2018
November 12
Major Version v2 Support Vector Machine Analysis
  • Support Vector Machine (SVM) Analysis added
  • MALDI-TOF Bruker© format support added
  • K-fold cross validation added
  • Categories section added for studies
June 4
Minor version v0.1.5
  • Reproducibility Analysis Module implementation
  • Peak findings improvements
  • Preprocessing improvements
    • Variance stabilization added
    • Mass filtering improvements
  • Alignment improvements
  • Automatic replication spectra added
April 2
Major Version v0.1 PLS-DA Module
  • Partial Least Squares Discriminant Analysis (PLS-DA) implementation
  • MALDI-TOF open format support improvements
  • Hierarchical Clustering (HC) improvements
  • Principal Components Analysis (PCA) improvements
  • Smoothing added
  • Baseline subtraction added
March 1
Official Release of RUO Clover Software

CloverBiosoft


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